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A Qualot Berry is a Berry that lowers a Pokémon's Defense EV total by 10. It also raises a Pokémon's happiness by 10, 5, or 2 depending on how much happiness the Pokémon initially has. It can be obtained from Berry trees, by using Forage on leaves with a Grass- or Bug-type Pokémon, or as a tier 1 special drop.
